The main goal of this study is to investigate the mechanism of wax precipitation through the petroleum pipelines. In order to achieve this target, this phenomenon has been examined from two different view points: theoretical and experimental study. The theory of this research seeks for predicting the quantity of wax deposition through petroleum pipelines. Mathematical model considers some important factors such as thermodynamic aspects of wax precipitation and fluid transport phenomena. In this paper the procedure for generating the mathematical model is described in detail. The second part of the research looks for doing some experiments with an oil- based cut which was synthesized by solving wax in toluene solvent. During the experiments, different parameters such as fluid flow rate, wax concentration, time effect and temperature difference between inlet fluid and pipe wall were considered at laboratory conditions. The results obtained from theoretical model were compared with experimental data. It was founded out that there is an acceptable match between experimental and theoretical data and to some extent; this confirms the validity of the model.